Ostarine MK-2866 Guide: How To Use, Side-Effects & Benefits

Ostarine is widely known as a powerful muscle builder and is currently being used by bodybuilders to boost their performance. 

The developers of Ostarine are still researching the benefits and side-effects of this compound. However, it still got huge popularity because of its muscle-building effects.

In this Ostarine guide, we will show you the benefits, side effects, and uses of this SARM.

Before we go into details, it’s essential to notice that the developers are still researching this compound on the effects and safety. Here is the latest clinical research on Ostarine.

We do not condone the usage of Ostarine, and we strictly advise NOT to buy, use, or sell it.

Ostarine is also known as Enobosarm or MK-2866 and is a Selective Androgen Receptor Modulator (SARM), which has been developed by Gtx inc. Researchers found out that it could possibly help with the treatment of muscle wasting diseases and osteoporosis.

They found out that it drastically could increase lean muscle mass without the adverse side effects of real anabolics.

That’s why it’s currently being used by bodybuilders to gain muscle mass or enhance their performance.

Ostarine falls in the category SARMs, just like LGD-4033 and RAD-140, which are both very well known compounds.

Ostarine enobosarm

It’s believed to be a ‘mild’ compound since research showed that it doesn’t suppress your natural testosterone as much as other SARMS, like testolone. 

MK-2866 is currently still in phase 2 trials and is still being researched for different purposes. Since it’s still an investigated drug, it isn’t available for the general public.

However, it’s still widely available on the internet and sold as a research chemical which is not for human consumption.

The FDA already warned the general public on bodybuilding supplements that contained SARMs.

What to Expect from Ostarine

When you compare Ostarine to other SARMs like Ligandrol and Testolone, you will notice that it’s a ‘mild’ compound in comparison to muscle gains but also side-effects.

Nonetheless, it’s one of the most used SARMs for either enhancing performance, increase muscle mass, and bone density.

These effects are all based on anecdotal experience and recent studies that have been released. Always keep in mind that this compound is only for research and laboratory uses only.

Increased Muscle Mass

Enobosarm is developed and researched for its positive effects on muscle loss for multiple diseases and also muscle loss in the elderly.

In a study done on the effects of Ostarine on lean muscle mass, it showed that it could increase muscle mass drastically. They used a dosage of 3mg a day and experienced no side effects at all.

Another study showed that after the use of 16 weeks at 1mg and 3mg showed an increase of 2-3 lbs of lean muscle mass.

MK-2866 is mostly developed to mimic the effects of real steroids but without the nasty side effects like gyno, testosterone suppression, and acne.

It has minimal side effects and has been proven to increase muscle mass in basically every study. 

MK-2866 is not something to take lightly, it most definitely works to enhance your performance in the gym. WADA also added it to it’s prohibited list since some athletes used it to enhance their performance.

Boost Fat Loss

Researchers found out that Ostarine could possibly help with increasing your standard metabolic rate. Meaning your body is able to process more calories, which leads to a greater deficit en possibly fat loss.

However, more research would be necessary to back these claims.

Improve Insulin Resistance

Ostarine could possibly help to improve insulin resistance and lower blood glucose levels. This could lead to better absorption of nutrients and increase muscle recovery. 

Ostarine effects

Ostarine Dosage Information

First of all, MK-2866 has shown to be effected at very low dosages. I am talking dosages as small as 1mg to 3mg.

However, an average dosage would be between 10 and 30mg a day. There is no scientific evidence that these are better dosages, however, anecdotally these dosages gave more muscle improvements.

We definitely wouldn’t advise anyone to go over the clinical dosage which is 3mg. These dosages have been proven to not give you any adverse effects. However, higher dosages could possibly mean more side-effects. 

I personally liked to use ostarine at 10mg for at least 8 weeks, while I was cutting down. It would greatly help me with muscle preservation and muscle hardening.

Ostarine is already effective at 1mg a day. However, as you can see, the lean body mass increased drastically when its increased to 3mg a day.

Therefore it’s believed that the ‘sweet spot’ is between 10 and 30mg. 

We do not recommend going above 3mg a day because the higher the dosage, the more side-effects you can experience. 

When searching for information about a typical cycle, you will see that it’s between 6-12 weeks and ranges from 10-30mg ostarine a day.

We recommend using a Post Cycle Therapy (PCT) like Rebirth PCT by Huge Nutrition to recover from the testosterone suppressive side effects and keep your new muscle gains.


The half-life of Ostarine is about 24 hours. That means if you plan on running a cycle, taking it once a day will be sufficient for having stable levels. So, it doesn’t matter if you take it in the morning or evening, just in a 24 hours time frame.

Can you stack Ostarine?

Stacking multiple compounds is something that could be beneficial but also very dangerous. Since Ostarine is a relatively new and not much data is available, we wouldn’t advise you to stack it.

You need to understand that when you add in another compound you are also increasing the chances of side-effects.

It’s therefore always advised to start with one compound and they slowly increase your dosage and then maybe add another compound

Most people stack MK-2866 with either GW-501516, S4-Andarine, or MK-677.

Increasing the dosage size could possibly increase the chance of liver toxicity. I would advise taking at least cycle support like DEFEND to protect your organs.

You could always stack it with something like BCAA’s or Creatine.

Does Ostarine have Side-Effects?

Most people who use MK-2866 do not experience any adverse side effects. However, researchers found that it could possibly have some adverse effects.

You could experience the following effects:

  • Headache 
  • Back Pain
  • High Blood Pressure
  • Suppress testosterone

Long term side effects still need to be investigated. The most known side effect is the suppression of your natural testosterone.

This means that you would need a PCT supplement to get your testosterone levels back up as soon as possible.

There are no signs that ostarine is liver or kidney toxic; however, if you would like to be sure you could always run a on-cycle support.

We wouldn’t recommend using ostarine since longterm side-effects have still not been investigated. Also, there hasn’t been done any large scale human trials yet.

If you are looking for something to gain muscle we would recommend Sapogenix by Huge Nutrition.

Does Ostarine Cause suppression?

While it doesn’t cause as much suppression as RAD-140, LGD-4033, or S23, it DOES suppress your natural testosterone. 

At dosages above 10mg, it definitely has proven to be suppressive. These effects are very mild and dosage dependant. 

The best thing to do is obviously a blood test before and after the cycle. However, if you are unable to do that you could always run a mild PCT like Rebirth.

Where To buy ostarine

Ostarine is not available for the general public until the FDA has approved it. The developers are still researching the safety, and human trails still need to be done on a larger scale.

When you search for it online, there are lots of different websites that claim to sell ostarine. However, these places do not have the license to sell it, and therefore we wouldn’t recommend buying it.


Ostarine is a mild SARM that is known for its muscle-building and performing-enhancing effects.

It’s currently still undergoing research and could possibly be introduced as a drug against muscle wasting diseases.

MK-2866 is being used by bodybuilders to build muscle, it’s so popular because it has almost no side-effects.

The average dosage lays between 10 and 30mg per day for a period of 8-12 weeks. 

A post cycle therapy is advised for users that are experiencing testosterone suppression side-effects.

While many users claim side-effects are minor, we do not advise you to use these kinds of compounds. 

There is a way safer and legal supplement available which can give you the same effect, which is Sapogenix.

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