Ostarine MK-2866 Guide: How To Use, Side-Effects & Benefits

Ostarine is widely known as a potent muscle-building compound and is currently being used by bodybuilders to boost performance. 

The developers of Ostarine are still researching the benefits and side-effects of this compound. However, it still got huge popularity because of its muscle-building effects.

This Ostarine guide will show you the benefits, side effects, and uses of this SARM.

Before we detail, it’s essential to notice that the developers are still researching this compound’s effects and safety. Here is the latest clinical research on Ostarine.

We do not condone the usage of Ostarine, and we strictly advise not to buy, use, or sell it.

Ostarine is also known as Enobosarm or MK-2866 and is a Selective Androgen Receptor Modulator (SARM), which has been developed by Gtx inc.

Researchers found out that it could possibly help with the treatment of muscle wasting diseases and osteoporosis.

They found out that it drastically could increase lean muscle mass without the adverse side effects of anabolic steroids.

This is the main reason why bodybuilders are currently using it to gain muscle mass or enhance their performance.

Ostarine falls in the category SARMs, which stands for Selective Androgen Receptor Modulator, just like LGD-4033 and RAD-140, which are both very well-known compounds.

Ostarine enobosarm

It’s believed to be a ‘mild’ compound since research showed that it doesn’t suppress your natural testosterone as much as other SARMS, like testolone. 

MK-2866 is currently still in phase 2 trials and is still being researched for different purposes. Since it’s still an investigated drug, it isn’t available for the general public.

However, it’s still widely available on the internet and sold as a research chemical that is not for human consumption.

The FDA already warned the general public on bodybuilding supplements that contained SARMs.

What to Expect from Ostarine

When you compare Ostarine to other SARMs like Ligandrol and Testolone, you will notice that it’s a ‘mild’ compound in comparison to muscle gains but also has side effects.

Nonetheless, it’s one of the most used SARMs for enhancing performance, increasing muscle mass, and bone density.

These effects are all based on anecdotal experience and recent studies that have been released. Always keep in mind that this compound is only for research and laboratory uses only.

Increased Muscle Mass

Enobosarm is developed and researched for its positive effects on muscle loss for multiple diseases and also muscle loss in the elderly.

In a study done on the effects of Ostarine on lean muscle mass, it showed that it could increase muscle mass drastically. They used a dosage of 3mg a day and experienced no side effects at all.

Another study showed that after the use of 16 weeks at 1mg and 3mg showed an increase of 2-3 lbs of lean muscle mass.

MK-2866 is mostly developed to mimic the effects of real steroids but without nasty side effects like gyno, testosterone suppression, and acne.

It has minimal side effects and has been proven to increase muscle mass in basically every study.  A recent study showed that both Ligandrol and Ostarine had beneficial effects on muscle structure and metabolism.

MK-2866 is not something to take lightly, it most definitely works to enhance your performance in the gym. WADA also added it to its prohibited list since some athletes used it to enhance their performance.

Boost Fat Loss

Researchers found out that Ostarine could possibly help with increasing your standard metabolic rate.

Meaning your body is able to process more calories, which leads to a greater deficit en possibly fat loss. Many users stack it with a thermogenic fat burner during a cut.

However, more research would be necessary to back these claims.

Improve Insulin Resistance

Ostarine could possibly help to improve insulin resistance and lower blood glucose levels. This could lead to better absorption of nutrients and increase muscle recovery. 

Ostarine effects

Ostarine Dosage Information

First of all, MK-2866 has been shown to be effective at very low dosages. I am talking dosages as small as 1mg to 3mg.

However, an average dosage would be between 10 and 30mg a day. There is no scientific evidence that these are better dosages. However, anecdotally these dosages gave more improvements like muscle mass, strength, and recovery.

We definitely wouldn’t advise anyone to go over the clinical dosage, which is 3mg. These dosages have been proven not to give you any adverse effects.

However, higher dosages could possibly mean more side effects. 

I personally liked to use ostarine at 10mg for at least 8 weeks while I was cutting down. It immensely helped me with muscle preservation and muscle hardening.

Ostarine dosage

Ostarine is already effective at 1mg a day. However, as you can see, the lean body mass increased drastically when the dosage is increased to 3mg a day.

Therefore many users claim that the ‘sweet spot is between 10 and 30mg per day.

Experienced users do not recommend going above 30mg a day because the higher the dosage, the more side effects you can experience. 

When searching for information about a typical cycle, you will see that it’s between 6-12 weeks and ranges from 10-30mg ostarine a day.

We recommend using a Post Cycle Therapy (PCT) like Rebirth PCT by Huge Supplements to recover from the testosterone suppressive side effects and keep your new muscle gains and also a cycle support supplement like Defend.


The half-life of Ostarine is about 24 hours. That means if you plan on running a cycle, taking it once a day will be sufficient for having stable levels.

So, it doesn’t matter if you take it in the morning or evening, just in a 24 hours time frame.

Can you stack Ostarine?

Stacking multiple compounds is something that could be beneficial but also very dangerous.

Since Ostarine is relatively new and not much data is available, we wouldn’t advise you to stack it with other unknown compounds.

You need to understand that when you add in another compound, you also increase the chances of side effects.

It’s therefore always advised to start with one compound, and they slowly increase your dosage and then maybe add another compound.

Most people stack MK-2866 with either GW-501516, S4-Andarine, or MK-677.

Increasing the dosage size could possibly increase the chance of liver toxicity.

If you stack SARMs, users advise taking a cycle support to protect vital organs like your liver and kidney.

Does Ostarine have Side-Effects?

Most people who use MK-2866 do not experience any adverse side effects. 

However, researchers found that it could possibly have multiple serious health issues. Recent studies revealed that Ostarine resulted in acute liver injury when using it for a prolonged period of time. The good news is that all subjects recovered after 3 months, but these are some serious side effects.

You could experience the following side effects:

  • Headache 
  • Back Pain
  • High Blood Pressure
  • Suppress testosterone
  • Liver Injury

Long-term side effects still need to be investigated. The most known side effect is the suppression of your natural testosterone.

This means that you would need a PCT supplement to get your testosterone levels back up as soon as possible.

We advise picking up one or two bottles of Rebirth, our to-go SARMs PCT.

There are multiple signs that Ostarine is liver and kidney toxic; if you would like to be save you should always run a on-cycle support.

We wouldn’t recommend using ostarine since long-term side effects have still not been investigated. Also, there haven’t been done any large-scale human trials yet.

If you are looking for something to gain muscle we would recommend Ecdysterone by Huge Supplements. This is a natural and way safer alternative, you also do not have to worry about adverse effects.

Does Ostarine Cause suppression?

Ostarine does suppress your natural hormone levels. While it’s not as suppressive as other SARMs such as RAD-140 or LGD-4033, it most definitively suppresses your natural testosterone.

Even at low dosages of 10mg per day, there will be a decrease in natural test production. Anecdotal experiences have shown us that the higher the dosage, the more suppression will occur.

That means you will need a post cycle therapy supplement; we advise going with Rebirth PCT. It’s the best PCT supplement for SARMs and can be ordered online.

You need to run Rebirth for a minimum of 4 weeks and a maximum of 8 weeks, depending on how you feel.

No matter what anybody tells you, Ostarine is suppressive and requires a post cycle therapy.

Where To buy ostarine

Many people have asked us where to buy ostarine. But the truth is, we advise against the use of  SARMs because of their unknown safety profile.

However, if you’re deadset on buying Ostarine, we would recommend using the most trusted source. When choosing this source, you will be 100% sure you will get quality products. You can buy Ostarine by clicking here.

The compound is still being researched, and human trials still need to be done on a larger scale. We don’t know what to expect from MK-2866 when it comes to long-term side effects.

And that’s why you should avoid this product. But don’t worry, we know you are looking for a product that can help you build mass and strength.

Something more potent, and we’ve found just the thing.

Ostarine Alternative

It’s called Ecdysterone, developed and sold by Huge Supplements. It contains Ecdysterone, which is a plant steroidal that is very potent for building lean muscle mass.

Skip buying ostarine and go for something like Ecdysterone.

We managed to gain nearly 8lb per week while on our cycle and have already planned the next 8-week cycle. It doesn’t require PCT either.


Ostarine is a mild SARM that is known for its muscle-building and performing-enhancing effects.

MK-2866 is being used by bodybuilders to build muscle; it’s so popular because it has almost no side-effects.

It’s currently still undergoing research, and that is why we don’t condone the use of it. It’s not safe to take.

The average dosage lays between 10 and 30mg per day for 8-12 weeks. This needs to be followed by a post-cycle therapy because otherwise, you are at risk of losing the muscle mass you’ve gained.

While many users claim side-effects are minor, we do not advise you to use these kinds of compounds. 

There is a way safer and legal supplement available, giving you the same effect, Ecdysterone. It’s helped us gain a significant amount of mass (7lbs) within just 8 weeks.

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