MK 677: Is Ibutamoren A Potent Growth Hormone Secretagogue?

An Introduction to MK 677 (Ibutamoren)


MK 677 or Ibutamoren is a growth hormone secretagogue and agonist of the ghrelin receptor being researched as a treatment for reduced levels of hormones.

It is said to increase Human Growth Hormone (HGH) and Insulin-like growth factor 1 (IGF-1) levels.

This article will support our claims and conclusions by clinical data and unbiased user reports that have tested this compound.

We will walk you through benefits, results, dosage information, side effects, and where to buy this compound.

At the time of writing, MK 677 had already gone through human clinical trials and was well-tolerated by the healthy participants (1).

MK 677 Benefits and Results

The main benefit of using MK 677 is that it raises both GH and IGF-1 levels in the body.

But, what does it mean to have increased levels of these hormones?

Well, Both Growth hormone and Insulin-Like Growth Factor-1 assist in the growth of muscle mass, recovery, strength, and performance.

This is even backed up by clinical data, as both hormones have shown to play an essential role in the regulation of muscle tissue development and maintenance (2).

When these hormones increase, a bodybuilder or athlete can benefit from this massively. The main benefit one will notice from this compound is the improved rate of recovery.

MK 677 Benefits Bodybuilding

Prolonged oral treatment with MK-677 also significantly increased the quality of REM sleep compared to placebo (3).

This is another exciting benefit, as sleep and rest are critical factors in the growth of muscle tissue.

Bodybuilders often stack Ibutamoren with selective androgen receptor modulators (SARMs) such as LGD-4033 or YK-11.

The reason for doing so is that SARMs have strong muscle-building capabilities, and combined with the increased GH & IGF-1 by MK 677, a massive improvement in overall performance will be noticed.

You can buy these compounds from Chemyo; they have the highest quality on the market right now.

How Do Higher HGH and IGF-1 Levels Affect the Body?

Human growth hormone and insulin-like growth factor-1 are both essential hormones responsible for regulating how our bodies grow and repair tissues.

The body’s natural production of HGH peaks during puberty and starts to decline in the early 20s. As HGH levels decline, though, the body begins to lose muscle mass, gain body fat and becomes more susceptible to diseases such as diabetes.

IGF-1 is another hormone that’s produced by the liver and is responsible for the growth and development of cells in the body. IGF-1 is also responsible for the production of new blood cells in the bone marrow and the regulation of blood sugar levels. Like HGH, IGF-1 levels can begin to drop as we age, leading to issues such as low testosterone, thyroid problems, and reduced muscle mass.

As the body’s natural production of these two hormones declines, many people turn to HGH and IGF-1 supplements to help maintain their health and vitality. However, as medical researchers continue to explore the benefits of MK 677, you may be able to experience naturally higher HGH and IGF-1 levels without having to supplement. This would help promote:

  • The growth of new muscle mass
  • Improve physical recovery after exercise
  • Increase overall body strength
  • Boost athletic performance as you age

Bodybuilders and athletes would especially benefit from taking a regular dose of MK 677. With higher levels of both hormones, you’d be able to develop stronger and healthier muscles without spending as much time in the gym.

Best of all, unlike with other compounds, such as anabolic steroids and testosterone supplements, you wouldn’t experience negative side effects or hormonal imbalances.

Other Ways That Taking MK 677 Can Benefit Bodybuilders

Along with the obvious effects of increased HGH and IGF-1 levels, researchers found that taking a prolonged oral dose of MK 677 led to an increase in the quality of participants’ REM sleep cycles. This suggests that it could act as a sleep aid for athletes who struggle to rest after exercising.

REM sleep, or rapid eye movement sleep, is one of the five stages of sleep. It typically only lasts for around 10 minutes but during that time, scientists believe we actively dream.

REM sleep is associated with increased brain activity as the brain is more active during REM sleep than during any other stage of sleep.

This sudden spike in brain activity has led neuroscientists to speculate that it’s one of the most important processes the brain can go through.

It’s believed to be important for learning and cementing memories, as well as repairing connections and tissues throughout the body. So, to put it plainly, if you’re not getting enough REM sleep, your muscles won’t have enough time to grow and repair.

MK 677 Dosage Data

After reviewing the benefits of using this compound, we will move on to the dosage information.

The dosage at which you’re going to run MK 677 is important because you’re going to need to know at which dosage you will experience.

According to clinical data, the optimal MK 677 dosage is between 20 to 25mg per day.

When we look at anecdotal user experiences, the average dosage also seems to be in line with the data.

MK677 Dosage

When we look at the clinical data we have available on this compound, the higher of a dose, the better the effects started to get. 

In some clinical studies, IGF-1 levels clearly increased in a dose-dependent manner (4). This is why many users often research with a higher dosage of 20 to 25mg per day.

Another thing worth mentioning is that Ibutamoren should be used for several weeks for its user to experience the benefits. The longer you use it, the more significant the results will get.

Administration of MK-677 25 mg resulted in a 60.1% increase in serum IGF-1 levels at 6 weeks and a 72.9% increase at 12 months (5).

As we can conclude from the clinical data, the longer Ibutamoren was administrated, the more IGF-1 increased. 

This is why it is generally advised to run your MK 677 dosage for more extended periods.

MK-677 Half-life

Half-life, or the time it takes for half of a dose of a medication to decay, can affect the duration of its effects. Drugs that are metabolized slowly have a longer duration than those that are metabolized quickly.

This is because it takes a longer time for the drug to be eliminated from the body. This is also why drugs with a longer half-life tend to have lower dosages.

Fortunately, the half-life of MK 677 is around 24 hours. This means that you can take a single dose every day and still experience the full range of its benefits.

We recommend taking it in the morning with other supplements or at night before bed. Because it has a full 24-hour half-life, it doesn’t really matter when you take it, as long as you stick to a regular schedule.

It will continue to stay in your system during that time, promoting the secretion and creation of more HGH and IGF-1. However, if you miss doses, you may lose out on some of its benefits.

If you miss a dose, we don’t recommend making it up. Instead, start back up on your cycle the next day.

Stacking MK-677

Stacking is a technique used by bodybuilders to improve the effectiveness of their training and muscle growth. Stacking involves the use of two or more supplements or drugs, usually with different mechanisms of action, in order to achieve a synergistic effect. This effect can be enhanced when different supplements or drugs are used at the same time.

Bodybuilders taking Ibutamoren often choose to stack it with other SARMs, such as LGD-4033 or YK-11. SARMs are a relatively new class of drugs that work by binding to the androgen receptor (AR), which is responsible for the development and maintenance of masculine characteristics.

By binding to the AR, SARMs are able to stimulate muscular growth and fat loss in a way that’s similar to testosterone. However, SARMs do not share the same side effects as testosterone and are much more selective in their action, meaning they only bind to the AR, not other receptors in the body.

This makes SARMs a safer and more effective alternative to testosterone replacement therapy.

Thanks to their similar benefits, stacking SARMs with MK 677 can create a dual-boost effect. When combined together, the increase in HGH and IGF-1 paired with SARMs results in a massive improvement in overall performance.

If you’re interested in stacking the two compounds, you can purchase them from Chemyo by clicking this link. They have the highest quality products on the market right now.

Does MK 677 Have Side Effects?

Although MK 677 has undergone human trials and is currently available through select compounding pharmacies, clinical data reports that it can cause a few side effects when taken for extended periods.

According to research in which elderly subjects received daily administration of MK 677 for two years, the most mentionable side effects were (5):

  • Increased Appetite – These symptoms were noted within the early stages of the study but soon subsided after several months of usage.
  • Water Retention – Participants experienced more fluid build-up in their bodies compared to placebo groups.
  • Muscle Soreness and Pain – Some participants reported feeling muscular soreness shortly after starting the trials, but these side effects soon disappeared after a few days.

As we went through user reports and clinical data, we found that these were the most common side effects.

They don’t account for the full range of possible side effects, but we felt that other accounts were too sporadic to include in our report. Other possible side effects included lethargy, which could be dealt with by taking MK 677 before bed.

If you choose to stack MK 677 with a SARM, you may also experience the following side effects:

  • Acne
  • Anxiety
  • Mood swings
  • High blood pressure

SARMs account for a wide range of products that are still being researched, so it’s hard to say for sure what the exact effects of stacking the two compounds may be.

If you feel that you’re experiencing any harmful side effects, trust your instincts and cut back on your cycle.

What we can say for sure is that MK 677 won’t interfere with your other hormones. Unlike other compounds, you won’t have to take post-cycle therapy (PCT) after completing a course of MK 677.

Simply finish out your cycle and then take a 4-week break. Within another month, you’ll be ready to start a new round of doses.

MK 677 For Sale

We at Nectac have tried several sites that have MK 677 for sale. Unfortunately, we quickly concluded that not every site sells a pure and quality product.

The only source we recommend buying this compound is Chemyo. We found that they have the most potent MK 677 for sale.

We experienced the classic symptoms such as increased appetite, better sleep, and recovery while researching it.

Our only complaint about Chemyo’s MK 677 is that it’s slightly more expensive than other options on the market. This isn’t much of a problem, though, considering that it’s arguably the highest quality out there.

Sure, you’ll pay a little more for it, but at the end of the day, it pays off. And, as you might already know, it’s vital to get a legitimate product for all your research.

While there are certainly other places to buy it, we don’t recommend looking elsewhere. A lot of competing sites are untrustworthy and sell impure hormone supplements. That is why we advise you to check out Chemyo, which we know sells guaranteed high-quality products.

MK 677 Frequently Asked Questions

We might have the answers if you still have questions about MK 677. Check out what some of our readers have asked and see if we answered your questions below.

What should i stack mk 677 with?

A lot of athletes choose to stack MK 677 with compounds that create similar effects. We’ve heard about bodybuilders stacking with mass-building SARMs, such as LGD4033 and RAD140.

Since MK 677 and SARMs can both help significantly increase muscular size, strength, and recovery rates, combining the two compounds can greatly amplify their individual effects.

If you’re considering stacking MK 677 with other supplements, just be sure to do your research ahead of time. Stacking products at the wrong doses can cause some nasty side effects, so make sure you know how much to take.

What is the best place to buy mk-677?

As far as we are concerned, Chemyo is the best place to buy high-quality MK 677. All of their products are tested by a third-party lab to guarantee that each batch of MK 677 meets quality control standards. You can personally check out the lab results on their official website or contact the labs directly.

It’s thanks to their stringent testing regulations that we’re convinced Chemyo is the best place to buy high-quality MK 677. You can visit the official Chemyo website and check out their full range of products.

How long can you stay on mk 677?

Based on anecdotal experience and clinical trials, you can take MK 677 for an extended period without experiencing harmful side effects.

Some clinical trials saw participants taking the compound for up to two years; however, we recommend taking it for no more than 6 months.

Keep in mind that it takes a few weeks to build up in your system before you start seeing results, and stick to the recommended dose.

What does ibutamoren mk 677 do?

According to clinical studies and anecdotal reports, Ibutamoren (MK 677) can help increase human growth hormone and insulin-like growth factor-1 levels.

At higher levels, these two hormones can help increase energy, reduce body fat, and promote muscular generation (2).

Should you take mk 677 on an empty stomach?

You can take MK 677 on an empty stomach but it won’t make much of a difference. Whether you opt to take it with food or without is entirely optional, but taking it on an empty stomach will not enhance the rate of absorption.


MK 677 is often mistaken for a SARM, but it is a highly effective growth hormone secretagogue. Over the past few years, it’s gotten a lot of attention for its ability to raise GH and IGF-1 levels. This can be beneficial for athletes who want to improve their recovery rates, muscular growth, and overall performance.

Also, compared to SARMs and other muscle-building supplements, Ibutamoren has to be taken for more extended periods for the results to start showing fully.

However, you can continue to take MK 677 for months at a time without experiencing serious side effects. Although side effects can occur during usage, they won’t interfere with your body’s hormones or chemistry.

If you want to try MK 677, we recommend purchasing from a verified vendor. Several vendors carry this compound, but we advise getting it from a reputable source such as Chemyo. They have the highest quality MK 677 we could find and even provide lab reports to back it up.

Several vendors carry this compound, but we advise getting it from a reputable source such as Chemyo.

Leave a Reply