The 4 Best Cycle Support Supplements: Protect Your Organs

When you use performance enhancers such as steroids and prohormones, you’re putting your body’s organs through a lot of stress.

Therefore, many use a potent cycle support supplement to help relieve the organs’ pressure and protect them.

Most people don’t realize that you’ll need a properly formulated product that will actually help protect your organs during a cycle.

We’ve tested and researched several of the most popular products and have put together a top 3 best cycle support supplements.

What Is A Cycle Support?


The name pretty much says it all. A cycle support is a product that protects you while you’re using a cycle of steroids, SARMs, or prohormones.

As you might already know, many anabolic steroids are toxic for the liver and other organs.

It’s crucial to combat the liver toxicity of these performance enhancers. You combat it by taking the recommended dosage of cycle support each day.

These products contain ingredients to help support healthy organs. Let’s take a look at the best-formulated cycle support products you should use during a cycle.

The 3 On Best Cycle Support Supplements

The following three products are considered to be the best-formulated on cycle support supplements.

If you’re running or planning a cycle, having one of these products on hand is an absolute must.

1. Defend Cycle Support

After testing and researching many different products and formulations, we’ve concluded that Defend by Huge Supplements is the best cycle support currently on the market.

The reason why it’s taken the top spot is that it contains high-quality ingredients at optimal dosages. 

We found that many supplements are missing one or two key ingredients when it comes to protection. That is not the case with Defend. 

It’s by far the most fully stacked and effective on cycle support.

We highly recommend getting one or two bottles of it if you plan on running a cycle.

Defend contains the following ingredients per 4 capsule-serving size:

  • Milk Thistle Extract (1000mg)
  • N-Acetyl-Cysteine (600mg)
  • Peppermint Leaf Powder (500mg)
  • TUDCA (250mg)
  • Red Clover (200mg)
  • Hawthorn Berry Extract (150mg)
  • Saw Palmetto Extract (250mg)

All these ingredients will contribute to keeping your organs healthy and protected during a cycle.

Especially TUDCA is an excellent ingredient for organ protection; in our opinion, it’s a must-have.

Defend can only be purchased from the official HugeSupplements website; it’s not available anywhere else.

You can also find post cycle therapy supplements on their website.

2. Advanced

Next up on our list is Advanced Cycle support by Iron Labs. This product is rather simply formulated but can still offer some form of protection.

It’s crucial to use on cycle support when you are using performance enhancers. They make sure you’ll be able to progress without having any issues.

Advanced contains the following ingredients per 2 capsule-serving size:

  • Milk Thistle (500mg)
  • N-Acetyl-Cysteine (400mg)
  • Hawthorne (300mg)
  • Saw Palmetto (200mg)
  • CoQ (100mg)
  • Celery Seed (75mg)
  • Grape Seed (75mg)

As you can see, it has some good ingredients. But it’s a lot weaker than the top-rated product Defend. 

Plus, it’s missing TUDCA – an essential ingredient.

Therefore, we would advise Defend over all other products.

Nonetheless, it’s still a product that can help you offer organ protection. It’s available from different online supplement retailer stores.

3. Blockade

Blockade cycle support

The third product on our list is Blockade cycle support by Assault Labs. It’s said to be a good product for those that want to stay safe while on performance enhancers.

Blockade contains the following ingredients per 3 capsule-serving size:

  • N-Acetyl-Cysteine (500mg)
  • Alpha Lipoic Acid (100mg)
  • Milk Thistle (500mg)
  • Hawthorn Berry Extract (350mg)
  • Grape Seed Extract (75mg)
  • ZMA (250mg)
  • Saw Palmetto (150mg)
  • CoQ10 (75mg)
  • Vitamin B6 (30mg)
  • Glucosamine Sulfate (500mg)

This product contains a wide variety of ingredients, which is a good thing. 

But, the ingredients such as Milk Thistle, Saw Palmetto, and NAC are relatively low dosed to offer the desired benefits.

If you do plan on using this product, we would advise only using it for milder cycles as it does not offer complete protection.

Blockade is available from several online supplement stores.

4. 5% Nutrition Liver & Organ Defender

5% Nutrition Liver & Organ Defender

Last but not least is the cycle support supplement from 5% Nutrition. They are known to provide hardcore bodybuilding supplements. This cycle support is widely available and contains all the necessary ingredients to help protect your vital organs. 

This product comes in a shocking 9-capsule serving size, the biggest on the list. While it contains important ingredients, it also comes with a certain price tag. If you have a bigger budget, this could be a good option. 

They divided the formula between heart support, liver support, prostate support, and skin support. As you can see, they combine many aspects of cycle support in one, and they have gone beyond that to add even more.

The only thing we didn’t like was that they didn’t include TUDCA and NAC, which are both staple ingredients in cycle support supplements. They did have Milk Thistle and Saw palmetto, which we know work very efficiently. 

Overall, an excellent option to consider, but a bit pricey compared to the other options on this list. 

Why You Should Use Cycle Support

Most people underestimate the importance of using a good cycle support supplement.

Of course, running performance enhancers can offer great mass and strength gains, but they also can cause negatives.

Most steroids and prohormones are hepatoxic, meaning they are toxic to the liver. It’s because of their chemical formulation and the fact that they take longer to pass the liver.

But they aren’t just toxic to the liver; they can also negatively impact blood pressure and other organs. 

However, we’re convinced that performance enhancers can be used safely with the right precautions.

You absolutely need something on hand to help you combat these side effects so that you stay safe. 

This is why you use a cycle support supplement – to help protect you so that you can continue gaining size without any issues.

Therefore, we always highly recommend stocking up on one such as Defend so that you’re good to go.

For natural muscle-building supplements, check out our articles on Epicatechin and Laxogenin.

Frequently Asked Questions

When to take cycle support?

We advise taking it with your first meal of the day. Make sure not to skip a dosage and be consistent. Check out the recommended dosage on the ingredient panel.

What is best cycle support for steroids?

When we look at product formulation, the best cycle support for steroids is Defend by Huge Supplements. It contains key ingredients such as TUDCA, Milk Thistle, and Hawthorn Berry to keep you safe.

How Can a Cycle Support Help?

These products contain ingredients that can help with supporting healthy organs, lipids, and blood pressure. This is crucial when you are running steroids, sarms, or prohormones.


If you want to use performance enhancers to increase mass and strength, it’s good to stock up on a cycle support supplement.

They’re formulated to help keep your organs protected and healthy. You should use them when you are taking steroids or prohormones.

We’ve shown you several high-quality cycle support products, the strongest one being Defend by Huge Supplements.

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